Endocrine Abstracts

Introduction: Hepatic metabolism of inhaled corticosteroids (ICS) takes place via cytochrome P450 3A4. Nevertheless, it can be decreased by enzyme inhibitors such as itraconazole or ritonavir, thus leading to an increase in the bioavailability of ICS. This can result in an accumulation of the steroid drug and a cushing’s syndrome.Case report: We present the case of a 48 year old woman with human immunodeficiency virus (HIV) infection on highly activ...

Objectives: Diabetes and obesity – Translational cardiovascular and obesityData regarding the prevalence of eating disorders (ED) and their influence on clinical outcomes among patients with type 2 diabetes (T2DM) are scarce. Our aim is to investigate the frequency of positive screening for ED and, specifically binge eating disorder (BED), in a T2DM sample. To analyse whether there are any differences among T2DM subjects with a positive screening for ED or BED.<p clas...

Background and aims: Obesity is linked to a low-grade and chronic systemic inflammation that improves after a significant weight loss. In the same way, depressive disorder has been suggested to be associated with systemic inflammation up regulation. We aimed to explore whether, after a significant weight loss, the presence of depressive symptoms was associated with differences in terms of inflammatory markers and quality of life compared with individuals without significant de...

Introduction: Information regarding eating disorders (ED) in postsurgical outcomes after bariatric surgery (BS) is scarce.Objectives: To analyze the effect of BS on ED and to investigate if ED influence clinical, biochemical or psychological outcomes.Methods: Sixty patients (78.3%♀, age 46.35±9.89, months since BS 46.28±28.1) who underwent BS, with a minimum follow up of 12 months, were evaluated cross-sectionally. ...

Background: There is an increasingly aware of strong associations between obesity and attention-deficit/hyperactivity disorder (ADHD), with high rates of ADHD (26–61%) in patients seeking weight loss. Psychological evaluation is mandatory in patients presenting for bariatric surgery (BS), although it is focused on eating disorders and depression, with data lacking on ADHD. ADHD could increase the risk for less successful results after surgery because of noncompliance with...

Introduction: Fahr’s syndrome in characterized by bilateral calcifications in basal ganglia, dentate nucleus and semioval center. Its clinical manifestations are a rigid hypokinetic syndrome, mood disorders and cognitive impairment. The most frequent aetiology of this syndrome is, together with idiopatic causes and congenital infections, calcium disorders, mainly primary hypoparathyroidism, accounting for up to 80% of all causes.Case report: A 57-ye...

Background: Depressive syndrome is a common psychiatric disorder in type 2 diabetic patients (T2DM), with negative outcomes in metabolic control and risk of developing cronic complications among these patients.Aims: i) To know the prevalence of depressive syndrome in a group of 113 T2DM seen consecutively in an endocrinologic outpatient clinic. ii) To analyze if there are any sociodemographic, clinical or biochemical differences between T2DM with positiv...

Adrenal ganglioneuroma (AGN) is a rare neoplasm derived from the neural crest. It can be found along the paravertebral sympathetic plexus. Mean age at presentation is below 20 years. Most patients with AGN are asymptomatic and diagnosis is usually incidental.Case report: Fourty three-year-old man with a personal history of hypertrophic cardiomyopathy in whom a follicular small cell non-Hodgkin lymphoma (NHL) was diagnosed after a biopsy of a left supracl...